CFS is a debilitating illness involving symptoms and abnormalities of the immune system, circulatory system, central nervous system, and hypothalamic-pituitary-adrenal axis. – Dr. Katrina Berne
CFS :: Chronic Fatigue Syndrome
Chronic Fatigue Syndrome (CFS) is not tiredness or extreme tiredness, but a severe flu-like illness that is usually precipitated by a virus or other infectious agents, often Infectious Mononucleosis/Glandular Fever(Epstein-Barr virus), Ross River fever or Toxoplasmosis here in Far North Queensland. Symptoms patients may suffer include headaches, memory and concentration problems, sore throat, muscle and joint pain, irritable bowel, disturbed sleep, exhaustion after minor effort, food allergies/sensitivities and sensitivity to bright light and noise. CFS is also known as Chronic Fatigue Immune Dysfunction Syndrome (mainly in the USA) and interchanges with Myalgic Encephalomyelitis (mainly in the UK).
Fibromyalgia Syndrome (FMS) patients suffer very similar symptoms but pain is much more prominent. Patients are diagnosed by the presence of 11 or more tender points (refer above link).
Both illnesses may be severely disabling, with some patients being largely bed bound. While many studies report higher levels of certain physical abnormalities in CFS/FM patients than in the healthy population, there currently isn't a validated diagnostic test. Diagnosis is made on the basis of symptom presentation.
The chronic fatigue syndrome is a clinically defined condition (1-4) characterized by severe disabling fatigue and a combination of symptoms that prominently features self-reported impairments in concentration and short-term memory, sleep disturbances, and musculoskeletal pain. Diagnosis of the chronic fatigue syndrome can be made only after alternative medical and psychiatric causes of chronic fatiguing illness have been excluded. No pathognomonic signs or diagnostic tests for this condition have been validated in scientific studies (5-7); moreover, no definitive treatments for it exist (8). Recent longitudinal studies suggest that some persons affected by the chronic fatigue syndrome improve with time but that most remain functionally impaired for several years (9, 10).
Ann Intern Med : Dec. 15; 1994 Vol. 121; #12: Pgs :953-959.How is CFS diagnosed?
There is no currently accepted, definitive test for CFS. The currently most widely accepted criteria for diagnosing CFS were published in the Annals of Internal Medicine, Vol 121, No 12, PP953 -959 on December 15, 1994. For a CFS diagnosis all other possible conditions must be excluded and the following 2 criteria must be present:
- Clinically evaluated, unexplained, persistent or relapsing chronic fatigue that is of new or definite onset (has not been lifelong); is not the result of ongoing exertion; is not substantially alleviated by rest; and results in substantial reduction in previous levels of occupational, educational, social, or personal activities.
- The concurrent occurrence of four or more of the following symptoms, all of which must have persisted or recurred during 6 or more consecutive months of illness and must not have predated the fatigue:
- self-reported impairment in short-term memory or concentration severe enough to cause substantial reduction in previous levels of occupational, educational, social, or personal activities,
- sore throat,
- tender cervical or axillary lymph nodes,
- muscle pain,
- multi-joint pain without joint swelling or redness,
- headaches of a new type, pattern, or severity,
- unrefreshing sleep, and
- post-exertional malaise lasting more than 24 hours.
What conditions should be excluded before a diagnosis of CFS is made? While you doctor should exclude the possibility of all the below conditions, particular attention should be paid to phosphate diabetes, sleep problems and coeliac's disease as these conditions are commonly missed by GPs.
- Neuromuscular Disease:
- Multiple Sclerosis,
- Myasthenia Gravis,
- Parkinson's Disease,
- rare muscle disorders.
- Chronic Infections:
- Brucellosis,
- Giardia,
- Hepatitis A,B,C,
- HIV,
- Leptospirosis hardjo,
- Lyme Disease,
- Parvovirus,
- Post-polio Syndrome,
- Toxocara (children),
- Toxoplasmosis.
- Gastric Disorders:
- Coeliac's Disease,
- Crohn's Disease,
- Food Allergies,
- Irritable Bowel Syndrome.
- Hormonal Imbalance:
- Addison's Disease,
- Fluid Retention Syndrome,
- Hypothyroidism,
- Haemochromatosis,
- Hypocalcaemia,
- Hyponatraemia,
- Thyrotoxicosis,
- Pituitary Tumour .
- Psychiatric Disorders:
- Anxiety,
- Depression,
- Post Traumatic Stress Disorder.
- Rheumatic Disorders:
- Fibromyalgia,
- Sjogren's Syndrome,
- Systemic Lupus Erythematosus.
- Miscellaneous:
- Alcohol abuse,
- Anaemia,
- Cervical Canal Stenosis,
- Chiari Syndrome,
- Hodgkin's Lymphoma,
- Organophosphate pesticides,
- Phosphate Diabetes,
- Sarcoidosis,
- Sick Building Syndrome,
- Sleep Apnoea and Narcolepsy,
- TB - Tuberculosis.
What causes CFS?
Endocrine dysfunction -particularly adrenal insufficiency, and Neurological dysfunction caused by the original virus/toxin
Who gets CFS?
CFS strikes people of all ages, races and socioeconomic backgrounds. Most diagnosed cases fall into the 15 to 45 age group (at onset). Women appear to be more likely to develop CFS, with some studies suggesting that up to two thirds of all PWCs are women. A 1980's media description of CFS as "yuppie flu" is completely inaccurate - it crosses all socioeconomic barriers, and, in fact, appears to be more common in the less well off.
How many people have CFS?
There are no precise figures of how many people have CFS. This is due to the fact that many people may be unsure of what they have, many doctors have hitherto not accepted that PWCs are ill and some PWCs simply 'drop out' when they cannot get any medical help.
In May 2002, a Working Group formed under the auspices of the Royal Australasian College of Physicians published a report that estimated from the published literature that between 0.2% and 0.7% of the population has CFS. This equates to between about 38,000 and 133,000 Australians. By way of comparison, about 22,000 Australians have been infected with HIV and about 15,000 have multiple sclerosis.
Are PWCs "malingering" or psychiatric cases?
Unfortunately, the name chronic fatigue syndrome unfairly implies that what is a quite painful, severe illness may only be tiredness or something imaginary.
A committee under the US Secretary for Health is currently considering a name change.
No serious researcher in the CFS area believes that they are looking at a trivial or imagined condition. In 1989, a New Zealand researcher, Dr L Simpson, had his research published in the New Zealand Medical Journal. It showed that PWCs, as a group, had larger numbers of misshapen red blood cells. Since then there have been more than 40 studies documenting various physical abnormalities observed in PWCs as a group. A full list of studies can be obtained from the Association's office.
Unfortunately, many doctors are not familiar with these studies. Doctors may also obtain the list of studies from the Association or special doctors' kit.
What are the symptoms?
The symptoms of CFS vary from person to person. The symptoms which are almost always present are exhaustion after a small amount of activity, difficulties with memory and concentration, headaches, face pallor particularly when symptoms are severe, and disrupted and disturbed sleep. Other symptoms can include sore throats, fever, raised glands, dizziness and balance problems, muscle weakness and pain, sore joints, sensitivity to noise and light, sensitivity to heat and cold, cognitive function problems (such as spatial disorientation and impairment of speech and reasoning), sensitivity to alcohol, irregular heartbeat, abdominal pain, irritable bowel, diarrhoea, dryness of the mouth and eyes, cold hands and feet, weight changes without changes in diet, anxiety and irritability, and new allergies or sensitivities to foods or chemicals.A more complete list is available here...
Can CFS be treated and what is the prognosis?
The vast majority of PWCs experience some improvement in the condition and
At least (and could be more if there were more accurate figures) 13% to 25% make a full recovery
Unfortunately, it does appear that about one fifth to one quarter of PWCs face a very long-term problem with the condition. The important thing is to take all sensible measures to get better and make sure that you are not one of them!
Is there any action to find a cure to CFS?
Yes! And your help is needed! Research teams at the University of Newcastle and the University of Adelaide are working on CFS but are woefully underfunded. Your donation and your voice are needed! Please join us to help. Donations to the projects can be made via State Associations.
"Fair Use" notice, if you wish to copy, reproduce or otherwise use material contained at this site; PLEASE READ.
